Chemical Structure : G2019S-LRRK2 inhibitor 22
Catalog No.: PC-49302Not For Human Use, Lab Use Only.
G2019S-LRRK2 inhibitor 22 is a novel potent, BBB-penetrant, G2019S-LRRK2 selective kinase inhibitor with IC50 of 4.6 nM, >700-fold selectivity over WT LRRK2.
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G2019S-LRRK2 inhibitor 22 is a novel potent, BBB-penetrant, G2019S-LRRK2 selective kinase inhibitor with IC50 of 4.6 nM, >700-fold selectivity over WT LRRK2.
M.Wt | 458.528 | |
Formula | C23H24F2N4O2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Leśniak RK, et al. Eur J Med Chem. 2022 Aug 24;242:114693.
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