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Chemical Structure : GB-110
CAS No.: 1252806-70-4
Catalog No.: PC-60319Not For Human Use, Lab Use Only.
GB-110 is a potent, non-peptidic agonist of PAR2 that selectively induces PAR2-mediated intracellular Ca(2+) release in HT29 cells with EC50 of 0.28 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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GB-110 is a potent, non-peptidic agonist of PAR2 that selectively induces PAR2-mediated intracellular Ca(2+) release in HT29 cells with EC50 of 0.28 uM.
GB-110 displays no activity for PAR-1 receptors.
| M.Wt | 608.784 | |
| Formula | C33H48N6O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-((S)-1-(((2S,3S)-1-((3-(4-(aminomethyl)piperidine-1-carbonyl)benzyl)amino)-3-methyl-1-oxopentan-2-yl)amino)-3-cyclohexyl-1-oxopropan-2-yl)isoxazole-5-carboxamide |
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1. Barry GD, et al. J Med Chem. 2010 Oct 28;53(20):7428-40.
2. Suen JY, et al. Br J Pharmacol. 2012 Mar;165(5):1413-23.
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