GDC-0339 |CAS:1428569-85-0 Probechem Biochemicals

Chemical Structure : GDC-0339

CAS No.: 1428569-85-0

GDC-0339 (GDC0339)

Catalog No.: PC-45110Not For Human Use, Lab Use Only.

GDC-0339 is a potent, orally bioavailable pan-Pim kinase inhibitor with Ki values of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively.

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5 mg	$458	In stock
10 mg	$728	In stock
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Biological Activity

GDC-0339 is a potent, orally bioavailable pan-Pim kinase inhibitor with Ki values of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively.

Physicochemical Properties

M.Wt	465.4952
Formula	C20H22F3N7OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 52 mg/mL
Chemical Name/SMILES	4-Thiazolecarboxamide, 5-amino-N-[5-[(4R,5R)-4-amino-5-fluorohexahydro-1H-azepin-1-yl]-1-methyl-1H-pyrazol-4-yl]-2-(2,6-difluorophenyl)-

References

1. Takahashi RH, et al. Drug Metab Dispos. 2017 Aug 8. pii: dmd.117.076786.

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GDC-0339 (GDC0339)

Biological Activity

Physicochemical Properties

References

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