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Cat. No. Product Name CAS No. Information
PC-35492

HS56

922050-57-5 HS56 (Pim-DAPK3 inhibitor HS56) is a potent, dual Pim/DAPK3 inhibitor with Ki of 72 nM (Pim-3) and 315 nM (DAPK3), shows micromolar potency toward Pim-1 and Pim-2 (Ki=1.5 and 17 uM).
PC-63507

SEL24-B489

1616359-00-2 SEL24-B489 (SEL24, MEN1703) is a potent, dual PIM and FLT3-ITD inhibitor with Kd of 2/2/3 nM for PIM1/2/3, Kd of 160/16 nM for FLT3-WT/FLT3-ITD, respectively.
PC-70113

LGB-321

1210416-93-5 LGB-321 (LGB321) is a potent and specific pan-Pim inhibitor with Ki of 1/2.1/0.8 pM for Pim1/2/3, respectively.
PC-45110

GDC-0339

1428569-85-0 GDC-0339 (GDC0339) is a novel small molecule pan-Pim kinase inhibitor that was discovered as a potential treatment for multiple myeloma.
PC-45605

PIM-447

1210608-43-7 A highly potent and selective inhibitor of pan-Pim with IC50s of 6/18/9 pM for Pim/1/2/3 respectively.
PC-38740

pan-PIM inhibitor 27

2698319-19-4 pan-PIM inhibitor 27 (SARxxxx92) is a potent, selective, orally bioavailable pan-PIM kinase inhibitor with IC50 of 1, 6 nM for Pim1 and Pim2, respectively.
PC-38739

DHPCC-9

1192248-37-5 DHPCC-9 is a selective Pim kinase inhibitor, inhibits Pim-1-dependent survival of cytokine-deprived myeloid cells (IC50=4-6 uM).

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