| Cat. No. |
Product Name |
Information |
| PC-63142 |
JP-11646
Pim2 inhibitor
|
JP-11646 (JP11646) is a novel potent, selective, non-ATP competitive Pim2 inhibitor with IC50 of 0.5/1/24 nM for Pim2/3/1, respectively. |
| PC-63141 |
NMS-P645
Pim inhibitor
|
NMS-P645 is a potent, selective inhibitor of pan-Pim kinases with IC50 of 3/73/12 nM for Pim1/2/3, respectively. |
| PC-63140 |
GNE-955
pan-Pim inhibitor
|
GNE-955 (GNE955) is a potent, selective pan-Pim inhibitor with Ki of 0.018/0.11/0.008 nM for Pim1/2/3, respectively. |
| PC-62787 |
Pim-IN-22m
Pim1/Pim2 inhibitor
|
Pim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively. |
| PC-70113 |
LGB-321
Pim inhibitor
|
LGB-321 (LGB321) is a potent and specific pan-Pim inhibitor with Ki of 1/2.1/0.8 pM for Pim1/2/3, respectively. |
| PC-42322 |
TP-3654
pan-Pim inhibitor
|
TP-3654 is a potent, selective, orally active second-generation PIM inhibitor with Ki of 5, 42 and 239 nM for Pim1, 2 and 3, respectively. |
| PC-45414 |
TCS PIM-1 1
Pim-1 inhibitor
|
TCS PIM-1 1 (SC 204330) is a potent, selective, ATP-competitive Pim-1 kinase inhibitor with IC50 of 50 nM; displays >400-fold selectivity over Pim-2 and MEK1/2. |
| PC-45416 |
CX-6258 hydrochloride hydrate
pan-Pim inhibitor
|
CX-6258 hydrochloride hydrate is a potent, selective, and orally efficacious pan-Pim inhibitor with IC50 of 5/25/16 nM for Pim1/2/3, respectively. |
| PC-45415 |
CX-6258
pan-Pim inhibitor
|
CX-6258 (CX6258) is a potent, selective, and orally efficacious pan-Pim inhibitor with IC50 of 5/25/16 nM for Pim1/2/3, respectively. |
| PC-42554 |
Pim1/AKK1-IN-1
Pim1/AKK1 inhibitor
|
Pim1/AKK1-IN-1 is a potent, multikinase inhibitor with Kd of 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK. |
| PC-45110 |
GDC-0339
Pim inhibitor
|
GDC-0339 is a potent, orally bioavailable pan-Pim kinase inhibitor with Ki values of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively. |
| PC-45606 |
PIM-447 dihydrochloride
Pim inhibitor
|
PIM-447 (LGH-447) dihydrochlorid is a highly potent and selective inhibitor of pan-Pim with IC50s of 6/18/9 pM for Pim/1/2/3 respectively. |
