TCS PIM-1 1 |CAS:491871-58-0 Probechem Biochemicals

Chemical Structure : TCS PIM-1 1

CAS No.: 491871-58-0

TCS PIM-1 1 (SC 204330;TCS PIM 1-1)

Catalog No.: PC-45414Not For Human Use, Lab Use Only.

TCS PIM-1 1 (SC 204330) is a potent, selective, ATP-competitive Pim-1 kinase inhibitor with IC50 of 50 nM; displays >400-fold selectivity over Pim-2 and MEK1/2.

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Biological Activity

TCS PIM-1 1 (SC 204330) is a potent, selective, ATP-competitive Pim-1 kinase inhibitor with IC50 of 50 nM; displays >400-fold selectivity over Pim-2 and MEK1/2.

Physicochemical Properties

M.Wt	367.1961
Formula	C18H11BrN2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 52 mg/mL
Chemical Name/SMILES	3-Pyridinecarbonitrile, 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-

References

1. Cheney IW, et al. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1679-83.

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TCS PIM-1 1 (SC 204330;TCS PIM 1-1)

Biological Activity

Physicochemical Properties

References

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