Chemical Structure : GDC-0575
CAS No.:
1196541-47-5
GDC-0575
(ARRY-575, RG7741, GDC0575)
Catalog No. : PC-60276Not For Human Use, Lab Use Only.
GDC-0575 (ARRY-575, RG7741) is a potent, selective and orally bioavailable Chk1 inhibitor with IC50 of 1.2 nM.
Packing Price Stock Quantity 5 mg $138 In stock 0 1 2 3 4 5 10 mg $218 In stock 0 1 2 3 4 5 25 mg $378 In stock 0 1 2 3 4 5 50 mg $598 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6027601
Biological Activity
GDC-0575 (ARRY-575, RG7741) is a potent, selective and orally bioavailable Chk1 inhibitor with IC50 of 1.2 nM.
Physicochemical Properties
M.Wt
377.286
Formula
C17H21BrN4O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-indol-3-yl)cyclopropanecarboxamide
References
1. Duan W, et al. Front Oncol.
2. Di Tullio A, et al. Nat Commun.
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