Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Wnt/Notch/Hedgehog-Autotaxin-GK442
GK442

Chemical Structure : GK442

CAS No.: 2047917-85-9

Add to Favorites

GK442 (GK-442)

Catalog No.: PC-23707Not For Human Use, Lab Use Only.

GK442 is a highly potent autotaxin inhibitor with IC50 of 60 nM.

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

GK442 is a highly potent autotaxin inhibitor with IC50 of 60 nM.
GK442 (30 mg/kg, i.p.) exhibited promising efficacy in a mouse model of pulmonary inflammation and fibrosis induced by bleomycin.

Physicochemical Properties

M.Wt 391.51
Formula C21H33N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-N1-(1-(Hydroxyamino)-1-oxononan-5-yl)-N6-phenyladipamide

References

1. Nikolaou A, et al. J Med Chem. 2018 Apr 26;61(8):3697-3711.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: