Chemical Structure : GLPG-2222
CAS No.:
1918143-53-9
GLPG-2222
(ABBV-2222;ABBV2222;GLPG2222)
Catalog No. : PC-60231Not For Human Use, Lab Use Only.
GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6023101
Biological Activity
GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM.
Physicochemical Properties
M.Wt
559.47
Formula
C28H21F4NO7
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-[(2R,4R)-4-({[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2H-chromen-2-yl]benzoic acid
References
1. Wang X, et al. J Med Chem.
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