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Chemical Structure : GLX481304
Catalog No.: PC-47046Not For Human Use, Lab Use Only.
GLX481304 is a specific small molecule inhibitor of Nox2 and Nox4 with IC50 values of 1.25 uM, shows negligible effects on Nox1.
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GLX481304 is a specific small molecule inhibitor of Nox2 and Nox4 with IC50 values of 1.25 uM, shows negligible effects on Nox1.
GLX481304 inhibits generation of reactive oxygen species in isolated cardiomyocytes.
GLX481304 improves cardiomyocyte contractility after hypoxia-reoxygenation.
GLX481304 improves whole heart contractility after hypoxia-reoxygenation in Langendorff perfused mouse heartsimproves whole heart contractility after hypoxia-reoxygenation in Langendorff perfused mouse hearts.
| M.Wt | 419.533 | |
| Formula | C23H29N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ferenc L M Szekeres, et al. Sci Rep. 2021 Jun 7;11(1):11970.
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