Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-NADPH Oxidase (NOX)-GLX481304
GLX481304

Chemical Structure : GLX481304

CAS No.: 701224-63-7

Add to Favorites

GLX481304 (GLX 481304)

Catalog No.: PC-47046Not For Human Use, Lab Use Only.

GLX481304 is a specific small molecule inhibitor of Nox2 and Nox4 with IC50 values of 1.25 uM, shows negligible effects on Nox1.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GLX481304 is a specific small molecule inhibitor of Nox2 and Nox4 with IC50 values of 1.25 uM, shows negligible effects on Nox1.
    GLX481304 inhibits generation of reactive oxygen species in isolated cardiomyocytes.
    GLX481304 improves cardiomyocyte contractility after hypoxia-reoxygenation.
    GLX481304 improves whole heart contractility after hypoxia-reoxygenation in Langendorff perfused mouse heartsimproves whole heart contractility after hypoxia-reoxygenation in Langendorff perfused mouse hearts.

    Physicochemical Properties

    M.Wt 419.533
    Formula C23H29N7O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N2-(3,4-dimethylphenyl)-6-((4-(3-methoxyphenyl)piperazin-1-yl)methyl)-1,3,5-triazine-2,4-diamine

    References

    1. Ferenc L M Szekeres, et al. Sci Rep. 2021 Jun 7;11(1):11970.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: