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Chemical Structure : GLX481372
Catalog No.: PC-73002Not For Human Use, Lab Use Only.
GLX481372 is a potent, selective NADPH oxidase 4 and 5 (Nox4 and Nox5) selective inhibitor with IC50 of 0.68 and 0.57 uM, respectively.
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GLX481372 is a potent, selective NADPH oxidase 4 and 5 (Nox4 and Nox5) selective inhibitor with IC50 of 0.68 and 0.57 uM, respectively.
GLX481372 weakly inhibited NOX1 and NOX2 with IC50 of >7 uM.
GLX481372 reduced human islet ROS production in human islet cells.
| M.Wt | 403.534 | |
| Formula | C23H29N7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wang X, et al. PLoS One. 2018 Sep 28;13(9):e0204271.
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