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Chemical Structure : GLX7013114
Catalog No.: PC-73001Not For Human Use, Lab Use Only.
GLX7013114 (GLX-7013114) is a novel selective NADPH oxidase 4 (Nox4) inhibitor with IC50 of 0.3 uM in in CJ Nox4 HEK 293 cell asays.
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GLX7013114 (GLX-7013114) is a novel selective NADPH oxidase 4 (Nox4) inhibitor with IC50 of 0.3 uM in in CJ Nox4 HEK 293 cell asays.
GLX7013114 displays no activity against Nox 1/2/3/5, as well as Glucose oxidase and Xanthine oxidase; does not display any redox activity.
GLX7013114 inhibits TGFβ-induced upregulation of mesenchymal genes.
GLX7013114 protected islet cells against both cytokines and high glucose + palmitate.
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