Chemical Structure : GNE-7915
CAS No.:
1351761-44-8
GNE-7915
(GNE7915, GNE 7915)
Catalog No. : PC-45424Not For Human Use, Lab Use Only.
GNE-7915 is a highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 1.9 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4542401
Biological Activity
GNE-7915 is a highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 1.9 nM.
Physicochemical Properties
M.Wt
443.3954
Formula
C19H21F4N5O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: 14.33 mg/mL
Chemical Name/SMILES
Methanone, [4-[[4-(ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl-
References
1. Estrada AA, et al. J Med Chem.
2. Fuji RN, et al. Sci Transl Med.
3. Kavanagh ME, et al. Bioorg Med Chem Lett.
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