Chemical Structure : GNE-7915 tosylate
CAS No.:
2070015-00-6
GNE-7915 tosylate
(GNE7915 tosylate, GNE 7915 tosylate)
Catalog No. : PC-45425Not For Human Use, Lab Use Only.
GNE-7915 tosylate (GNE7915 tosylate) is a highly potent, selective, and brain-penetrable LRRK2 inhibitor with IC50 of 1.9 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4542501
Biological Activity
GNE-7915 tosylate (GNE7915 tosylate) is a highly potent, selective, and brain-penetrable LRRK2 inhibitor with IC50 of 1.9 nM.
Physicochemical Properties
M.Wt
615.597
Formula
C26H29F4N5O6S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Methanone, [4-[[4-(ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl-, 4-methylbenzenesulfonate (1:1)
References
1. Estrada AA, et al. J Med Chem.
2. Fuji RN, et al. Sci Transl Med.
3. Kavanagh ME, et al. Bioorg Med Chem Lett.
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