Chemical Structure : GNF179
CAS No.: 1261114-01-5
Catalog No.: PC-47013Not For Human Use, Lab Use Only.
GNF179 is an antimalarial imidazolopiperazine, possesses low nanomolar potency against P. falciparum liver stages, asexual blood stages and sexual stage gametocytes.
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GNF179 (KAF179) is an antimalarial imidazolopiperazine, possesses low nanomolar potency against P. falciparum liver stages, asexual blood stages and sexual stage gametocytes.
M.Wt | 427.908 | |
Formula | C22H23ClFN5O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-amino-1-(3-((4-chlorophenyl)amino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethan-1-one |
1. Meister S, et al. Science. 2011 Dec 9;334(6061):1372-7.
2. Lim MY, et al. Nat Microbiol. 2016 Sep 19;1:16166.
3. Magistrado PA, et al. ACS Infect Dis. 2016 Nov 11;2(11):816-826.
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