GNF179 (KAF179)

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Chemical Structure : GNF179

CAS No.: 1261114-01-5

Catalog No.: PC-47013Not For Human Use, Lab Use Only.

GNF179 is an antimalarial imidazolopiperazine, possesses low nanomolar potency against P. falciparum liver stages, asexual blood stages and sexual stage gametocytes.

Packing	Price	Stock
5 mg	$258	In stock
10 mg	$398	In stock
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Biological Activity

GNF179 (KAF179) is an antimalarial imidazolopiperazine, possesses low nanomolar potency against P. falciparum liver stages, asexual blood stages and sexual stage gametocytes.

Physicochemical Properties

M.Wt	427.908
Formula	C22H23ClFN5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-amino-1-(3-((4-chlorophenyl)amino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethan-1-one

References

1. Meister S, et al. Science. 2011 Dec 9;334(6061):1372-7.

2. Lim MY, et al. Nat Microbiol. 2016 Sep 19;1:16166.

3. Magistrado PA, et al. ACS Infect Dis. 2016 Nov 11;2(11):816-826.

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GNF179 (KAF179)

Biological Activity

Physicochemical Properties

References

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