Chemical Structure : GPI-1046
CAS No.:
186452-09-5
GPI-1046
(GPI1046;GPI 1046)
Catalog No. : PC-63577Not For Human Use, Lab Use Only.
GPI-1046 is a non-immunosuppressive ligand of the immunophilin FKBP12.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6357701
Biological Activity
GPI-1046 is a non-immunosuppressive ligand of the immunophilin FKBP12.
Physicochemical Properties
M.Wt
360.454
Formula
C20H28N2O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3-(3-pyridyl)-1-propyl (2S)-1-(3,3-dimethyl-1,2-dioxopentyl)-2-pyrrolidinecarboxylate
References
1. Sauer H, et al. Brain Res. 1999 Sep 18;842(1):109-18.
2. Burnett AL, et al. Urology. 2005 May;65(5):1003-7.
3. Sari Y, et al. Neuroscience. 2012 Dec 27;227:327-35.
4. Tampe B, et al. J Clin Invest. 2018 Apr 17. pii: 89632.
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