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GPR83 agonist CPD1

Chemical Structure : GPR83 agonist CPD1

CAS No.: 924836-07-7

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GPR83 agonist CPD1

Catalog No.: PC-26013Not For Human Use, Lab Use Only.

GPR83 agonist CPD1 is a potent, selective small molecule GPR83 agonist with binding IC50 of 10 nM, induces dose-dependent increases in intracellular Ca+2 release in CHO cells expressing mouse GPR83 with EC50 of 74 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GPR83 agonist CPD1 is a potent, selective small molecule GPR83 agonist with binding IC50 of 10 nM, induces dose-dependent increases in intracellular Ca+2 release in CHO cells expressing mouse GPR83 with EC50 of 74 nM.
    CPD1 decreases morphine antinociception in mice.

    Physicochemical Properties

    M.Wt 369.86
    Formula C20H16ClNO2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    7-(2-((4-chlorobenzyl)oxy)phenyl)-6,7-dihydrothieno[3,2-b]pyridin-5(4H)-one

    References

    1. Gomes I, et al. Mol Pharmacol. 2025 Nov 24;108(1):100092.

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