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Chemical Structure : GPRP acetate
CAS No.: 157009-81-9
Catalog No.: PC-47483Not For Human Use, Lab Use Only.
GPRP acetate (Pefabloc FG) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin, inhibits the spontaneous polymerization of fibrin monomers.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $228 | In stock | |
| 50 mg | $388 | In stock | |
| 100 mg | Get quote |
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GPRP acetate (Pefabloc FG) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin, inhibits the spontaneous polymerization of fibrin monomers.
GPRP acetate also inhibits ADP-induced platelet aggregation with IC50 of 3 mM.
GPRP acetate binds to the fibrinogen D domain, and inhibits the ability of fibrinogen to bind to the platelet membrane glycoprotein GPIIb/IIIa.
| M.Wt | 485.5346 | |
| Formula | C20H35N7O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
100 mM in H2O |
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| Chemical Name/SMILES |
L-Proline, glycyl-L-prolyl-L-arginyl-, acetate (1:1) |
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1. Laudano AP, et al. Proc Natl Acad Sci U S A. 1978 Jul;75(7):3085-9.
2. Plow EF, et al. Proc Natl Acad Sci U S A. 1982 Jun;79(12):3711-5.
3. Adelman B, et al. Circ Res. 1990 Oct;67(4):941-7.
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