GSK-2807 |Cas:N/A Buy GSK-2807 from ProbeChem, Global Biochemicals Supplier

Chemical Structure : GSK-2807

GSK-2807 (GSK 2807;GSK2807)

Catalog No.: PC-70109Not For Human Use, Lab Use Only.

GSK-2807 (GSK 2807, GSK2807) is a potent and selective, SAM-competitive inhibitor of SMYD3 with Ki of 14 nM.

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Biological Activity

GSK-2807 (GSK 2807, GSK2807) is a potent and selective, SAM-competitive inhibitor of SMYD3 with Ki of 14 nM; displays 24-fold selectivity over SMYD2, and a panel of PRMTs including: PRMT1, PRMT4, PRMT5, NSD2, NSD3, DOT1L, G9a, and ASH1L.

Physicochemical Properties

M.Wt	452.516
Formula	C19H32N8O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(3-(dimethylamino)propyl)amino)butanoic acid

References

1. Van Aller GS, et al. Structure. 2016 May 3;24(5):774-81.

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GSK-2807 (GSK 2807;GSK2807)

Biological Activity

Physicochemical Properties

References

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