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GSK-3/CDK5/CDK2-IN-1

Chemical Structure : GSK-3/CDK5/CDK2-IN-1

CAS No.: 395074-72-3

GSK-3/CDK5/CDK2-IN-1

Catalog No.: PC-38600Not For Human Use, Lab Use Only.

GSK-3/CDK5/CDK2-IN-1 is an inhibitor of CDK5, CDK2 and GSK-3, inhibits the phosphorylation of Cdk5 peptide substrate phosphorylation with IC50 of <50 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GSK-3/CDK5/CDK2-IN-1 is an inhibitor of CDK5, CDK2 and GSK-3, inhibits the phosphorylation of Cdk5 peptide substrate phosphorylation with IC50 of <50 uM.

Physicochemical Properties

M.Wt 362.42
Formula C21H22N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[1-[cis-3-(Acetylamino)cyclobutyl]-1H-imidazol-4-yl]-2-naphthaleneacetamide

References

1. Patent WO2002010141A1, example 9a.

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