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Chemical Structure : GSK-5498A
CAS No.: 1253186-49-0
Catalog No.: PC-43089Not For Human Use, Lab Use Only.
GSK-5498A is a potent, selective small molecule blocker of Calcium-Release Activated Calcium (CRAC) channel with IC50 of 1 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $288 | In stock | |
| 10 mg | $428 | In stock | |
| 25 mg | $728 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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GSK-5498A is a potent, selective small molecule blocker of Calcium-Release Activated Calcium (CRAC) channel with IC50 of 1 uM.
GSK-5498A completely inhibits calcium influx through CRAC channels.
GSK-5498A inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells from multiple human and rat preparations.
| M.Wt | 399.2899 | |
| Formula | C18H11F6N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzamide, 2,6-difluoro-N-[1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-3-yl]- |
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1. Rice LV, et al. Eur J Pharmacol. 2013 Mar 15;704(1-3):49-57.
2. Chen J, et al. J Physiol. 2017 May 15;595(10):3203-3218.
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