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Chemical Structure : GSK023
Catalog No.: PC-21329Not For Human Use, Lab Use Only.
GSK023 is a potent, selective BET BD1 domain inhibitor with pIC50 of 7.8 against BRD4 BD1, >100-fold selective over BD2.
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GSK023 is a potent, selective BET BD1 domain inhibitor with pIC50 of 7.8 against BRD4 BD1, >100-fold selective over BD2.
GSK023 decreases the levels of MCP-1, IL-8, IL-1, IL-10, M-CSF, and IL-6 in human primary T cells.
| M.Wt | 489.66 | |
| Formula | C29H39N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bradley E, et al. J Med Chem. 2023 Nov 15. doi: 10.1021/acs.jmedchem.3c00906.
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