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GSK 214096

Chemical Structure : GSK 214096

CAS No.: 716354-87-9

GSK 214096 (GSK214096;GSK-214096)

Catalog No.: PC-61089Not For Human Use, Lab Use Only.

GSK 214096 potent, selective CCR5 antagonist and HIV-1 entry inhibitor, inhibits HIV-1 glycoprotein 120 (gp120) binds to the CD4+ T-cell receptor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GSK 214096 potent, selective CCR5 antagonist and HIV-1 entry inhibitor, inhibits HIV-1 glycoprotein 120 (gp120) binds to the CD4+ T-cell receptor.

    Physicochemical Properties

    M.Wt 754.787
    Formula C39H46Cl2FN5O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(tert-butyl)-2,4-dichloro-3-(4-(3-fluorophenyl)-4-(2-((1R,3r,5S)-3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)piperidine-1-carbonyl)benzenesulfonamide

    References

    1. Kazmierski WM, et al. ACS Med Chem Lett. 2014 Oct 28;5(12):1296-9.

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