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Chemical Structure : GSK2646264
CAS No.: 1398695-47-0
Catalog No.: PC-35689Not For Human Use, Lab Use Only.
GSK2646264 (GSK-2646264) is a potent, selective Spleen Tyrosine Kinase (Syk) inhibitor with pIC50 of 7.1, >300-fold selectivity over Autota B.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $398 | In stock | |
| 5 mg | $598 | In stock | |
| 10 mg | $898 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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GSK2646264 (GSK-2646264) is a potent, selective Spleen Tyrosine Kinase (Syk) inhibitor with pIC50 of 7.1, >300-fold selectivity over Autota B。
GSK2646264 inhibits anti-IgM induced Erk1/2 phosphorylation in Ramos B cells with pIC50 of 6.7.
| M.Wt | 374.484 | |
| Formula | C24H26N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
7-(2-methoxy-6-((4-methylpyridin-2-yl)methoxy)phenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine |
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1. Barker MD, et al. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3458-3462.
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