GSK3β inhibitor MJ34 | GSK3β inhibitor

Chemical Structure : GSK3β inhibitor MJ34

GSK3β inhibitor MJ34 (ISO-1479)

Catalog No.: PC-22537Not For Human Use, Lab Use Only.

GSK3β inhibitor MJ34 (ISO-1479) is a potent, GSK3β selective inhibitor with IC50 of 15.4 nM, significantly reduces growth and survival of human mutant KRas dependent pancreatic tumors.

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Biological Activity

GSK3β inhibitor MJ34 (ISO-1479) is a potent, GSK3β selective inhibitor with IC50 of 15.4 nM, significantly reduces growth and survival of human mutant KRas dependent pancreatic tumors.

Physicochemical Properties

M.Wt	315.38
Formula	C19H17N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(5-(2-ethylphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine

References

1. Ayaz MO, et al. Life Sci. 2024 Aug 15;351:122840.

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GSK3β inhibitor MJ34 (ISO-1479)

Biological Activity

Physicochemical Properties

References

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