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GSK3039294

Chemical Structure : GSK3039294

CAS No.: 1819986-22-5

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GSK3039294 (GSK 3039294, GSK294)

Catalog No.: PC-63133Not For Human Use, Lab Use Only.

GSK3039294 is an orally available small molecule inhibitor of serum amyloid P component (SAP) binding to amyloid fibrils for the depletion of serum amyloid-P (SAP) component from the circulation, an orally bioavailable pro‐drug of miridesap.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GSK3039294 is an orally available small molecule inhibitor of serum amyloid P component (SAP) binding to amyloid fibrils for the depletion of serum amyloid-P (SAP) component from the circulation, an orally bioavailable pro‐drug of miridesap.

    Physicochemical Properties

    M.Wt 656.682
    Formula C30H44N2O14
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    bis(((((tetrahydro-2H-pyran-4-yl)oxy)carbonyl)oxy)methyl) adipoyl(R)-di-D-prolinate

    References

    1. Duncan Richards, et al. Br J Pharmacol. 2020 Apr;177(8):1853-1864.

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