GSK3491943 | TRPV4 inhibitor | Probechem Biochemicals

Chemical Structure : GSK3491943

Catalog No.: PC-22742Not For Human Use, Lab Use Only.

GSK3491943 is a potent, selective TRPV4 inhibitor with IC50 of 3.2 nM (hTRPV4).

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

GSK3491943 is a potent, selective TRPV4 inhibitor with IC50 of 3.2 nM (hTRPV4).

M.Wt	491.35
Formula	C18H16Cl2N2O6S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Chloro-4-(((3R,4S)-4-((4-chlorophenyl)sulfonyl)-3-hydroxy-3-(hydroxymethyl)pyrrolidin-1-yl)sulfonyl)benzonitrile

1. Joseph E Pero, et al. J Med Chem. 2018 Dec 27;61(24):11209-11220.

2. Carl A Brooks, et al. J Med Chem. 2019 Oct 24;62(20):9270-9280.