GSK549 | BET BD2 inhibitor | Probechem Biochemicals

Chemical Structure : GSK549

Catalog No.: PC-72180Not For Human Use, Lab Use Only.

GSK549 (GSK-549) is a potent, highly selective, BD2 domain-selective BET inhibitor with pIC50 of 7.8 (BRD4 BD2), 1150-fold selectivity over BD1.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

GSK549 (GSK-549) is a potent, highly selective, BD2 domain-selective BET inhibitor with pIC50 of 7.8 (BRD4 BD2), 1150-fold selectivity over BD1.

M.Wt	366.421
Formula	C20H22N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N5-Cyclopropyl-1-(indolin-4-ylmethyl)-N3 -methyl-2-oxo-1,2-dihydropyridine-3,5-dicarboxamide

1. Seal JT, et al. J Med Chem. 2020 Sep 10;63(17):9093-9126.

2. Harrison LA, et al. J Med Chem. 2021 Aug 12;64(15):10742-10771.