GSK690 | LSD1 inhibitor | Probechem Biochemicals

Chemical Structure : GSK690

CAS No.: 2101305-84-2

Catalog No.: PC-61745Not For Human Use, Lab Use Only.

GSK690 is a reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM.

Packing	Price	Stock
5 mg	$138	In stock
10 mg	$218	In stock
25 mg	$388	In stock
50 mg	$598	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GSK690 is a reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM.

M.Wt	369.468
Formula	C24H23N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-4-[5-(Pyrrolidin-3-ylmethoxy)-2-p-tolyl-pyridin-3-yl]-benzonitrile

1. Mould DP, et al. J Med Chem. 2017 Sep 11. doi: 10.1021/acs.jmedchem.7b00462.

2. Mould DP, et al. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4755-4759.

3. McGrath JP, et al. Cancer Res. 2016 Apr 1;76(7):1975-88.