You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Histone Demethylase-GSK690
GSK690

Chemical Structure : GSK690

CAS No.: 2101305-84-2

GSK690 (GSK 690, GSK-690)

Catalog No.: PC-61745Not For Human Use, Lab Use Only.

GSK690 is a reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM.

Packing Price Stock Quantity
5 mg Get quote
10 mg Get quote
25 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GSK690 is a reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM.

    Physicochemical Properties

    M.Wt 369.468
    Formula C24H23N3O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-4-[5-(Pyrrolidin-3-ylmethoxy)-2-p-tolyl-pyridin-3-yl]-benzonitrile

    References

    1. Mould DP, et al. J Med Chem. 2017 Sep 11. doi: 10.1021/acs.jmedchem.7b00462.

    2. Mould DP, et al. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4755-4759.

    3. McGrath JP, et al. Cancer Res. 2016 Apr 1;76(7):1975-88.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: