Chemical Structure : GSK690 hydrochloride
CAS No.: 2436760-79-9
Catalog No.: PC-24227Not For Human Use, Lab Use Only.
GSK690 hydrochloride is a potent, reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM.
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GSK690 hydrochloride is a potent, reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM.
M.Wt | 405.93 | |
Formula | C24H24ClN3O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-4-[5-(Pyrrolidin-3-ylmethoxy)-2-p-tolyl-pyridin-3-yl]-benzonitrile hydrochloride |
1. Mould DP, et al. J Med Chem. 2017 Sep 11. doi: 10.1021/acs.jmedchem.7b00462.
2. McGrath JP, et al. Cancer Res. 2016 Apr 1;76(7):1975-88.
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