GSK717 | NOD2 inhibitor | Probechem Biochemicals

Chemical Structure : GSK717

CAS No.: 1595278-21-9

GSK717 (GSK-717)

Catalog No.: PC-38557Not For Human Use, Lab Use Only.

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor, inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, has an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.

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25 mg	$258	In stock
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Biological Activity

GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor, inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, has an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.

Physicochemical Properties

M.Wt	452.55
Formula	C28H28N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-[2-(Benzoylmethylamino)ethyl]-N-(2,3-dihydro-1H-inden-5-yl)-1H-benzimidazole-1-acetamide

References

1. Rickard DJ, et al. PLoS One. 2013 Aug 1;8(8):e69619.

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GSK717 (GSK-717)

Biological Activity

Physicochemical Properties

References

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