Chemical Structure : GW405833 hydrochloride
CAS No.:
1202865-22-2
GW405833 hydrochloride
(GW-405833;GW 405833)
Catalog No. : PC-60728Not For Human Use, Lab Use Only.
GW405833 is a potent, selective cannabinoid receptor CB2 agonist with Ki of 3.6 nM, 1200-fold selectivity over CB1.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6072801
Biological Activity
GW405833 is a potent, selective cannabinoid receptor CB2 agonist with Ki of 3.6 nM, 1200-fold selectivity over CB1.
Physicochemical Properties
M.Wt
483.814
Formula
C23H25Cl3N2O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(2,3-dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-morpholin-4-yl-ethyl)-indol-1-yl]-methanone hydrochloride
References
1. Valenzano KJ, et al. Neuropharmacology. 2005 Apr;48(5):658-72.
2. Whiteside GT, et al. Eur J Pharmacol. 2005 Dec 28;528(1-3):65-72.
3. Hu B, et al. Pain. 2009 Jun;143(3):206-12.
4. Li AL, et al. J Pharmacol Exp Ther. 2017 Aug;362(2):296-305.
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