Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Gingerenone A
CAS No.: 128700-97-0
Catalog No.: PC-60874Not For Human Use, Lab Use Only.
Gingerenone A is a dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Gingerenone A is a dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells.
Gingerenone A induces apoptosis in cancer cells and suppresses tumor growth in vivo associated with relative phosphorylation levels of JAK2 and S6K1.
Gingerenone A suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice.
| M.Wt | 356.418 | |
| Formula | C21H24O5 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E)- |
|
1. Byun S, et al. J Biol Chem. 2015 Sep 25;290(39):23553-62.
2. Kim HJ, et al. J Cell Biochem. 2018 Jan;119(1):260-268.
3. Suk S, et al. Mol Nutr Food Res. 2017 Oct;61(10).
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
