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Girocitinib

Chemical Structure : Girocitinib

CAS No.: 2222137-79-1

Girocitinib (TLL-018, TLL018)

Catalog No.: PC-28437Not For Human Use, Lab Use Only.

Girocitinib (TLL-018) is a highly selective, orally active small-molecule JAK1/TYK2 inhibitor, blocks TYK2 and JAK1 involved in inflammation.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Girocitinib (TLL-018) is a highly selective, orally active small-molecule JAK1/TYK2 inhibitor, blocks TYK2 and JAK1 involved in inflammation.

Physicochemical Properties

M.Wt 326.36
Formula C17H18N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((2R,5S)-5-(2-((R)-1-hydroxyethyl)-1H-furo[3,2-b]imidazo[4,5-d]pyridin-1-yl)tetrahydro-2H-pyran-2-yl)acetonitrile

References

1. Chen JQ, et al. Br J Dermatol. 2025 Sep 18;193(4):670-677.

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