Chemical Structure : Glecirasib
CAS No.: 2657613-87-9
Catalog No.: PC-22626Not For Human Use, Lab Use Only.
Glecirasib (JAB-21822) is a highly selective, covalent oral KRAS G12C inhibitor, demonstrated promising clinical activity in NSCLC and CRC.
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Glecirasib (JAB-21822) is a highly selective, covalent oral KRAS G12C inhibitor, demonstrated promising clinical activity in NSCLC and CRC.
M.Wt | 640.04 | |
Formula | C31H26ClF4N7O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
7-(2-Amino-3,4,5,6-tetrafluorophenyl)-6-chloro-1,2-dihydro-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-2-oxo-4-[4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-1,8-naphthyridine-3-carbonitrile |
1. Jian Li, et al. 2024 ASCO.Volume 42, Number 3_suppl
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