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GlyH-101

Chemical Structure : GlyH-101

CAS No.: 328541-79-3

GlyH-101 (GlyH 101, GlyH101)

Catalog No.: PC-45455Not For Human Use, Lab Use Only.

GlyH-101 is a potent CFTR inhibitor with Ki of 4.3 uM.

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10 mg $128 In stock
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50 mg $358 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GlyH-101 is a potent CFTR inhibitor with Ki of 4.3 uM.
GlyH-101 rapidly and reversibly inhibited forskolin-induced hyperpolarization in nasal potential differences in mice.
GlyH-101 effectively reduces cholera toxin-induced intestinal fluid secretion in a closed-loop model of cholera.

Physicochemical Properties

M.Wt 493.1487
Formula C19H15Br2N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 58 mg/mL

Chemical Name/SMILES

Glycine, N-2-naphthalenyl-, 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide

References

1. Muanprasat C, et al. J Gen Physiol. 2004 Aug;124(2):125-37.

2. Norimatsu Y, et al. Mol Pharmacol. 2012 Dec;82(6):1042-55.

3. Barman PP, et al. Biochem Biophys Res Commun. 2011 Apr 29;408(1):12-7.

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