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H210

Chemical Structure : H210

CAS No.:

H210 (dual Mdm2/MdmX inhibitor H210)

Catalog No.: PC-38075Not For Human Use, Lab Use Only.

H210 is a potent dual Mdm2/MdmX inhibitor with Ki of 9.66/2.89 nM, respectively..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

H210 is a potent dual Mdm2/MdmX inhibitor with Ki of 9.66/2.89 nM, respectively.

Physicochemical Properties

M.Wt 575.874
Formula C30H21Cl3N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-((4S,5R)-5-(4-chlorophenyl)-4-(3,5-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-yl)-1-phenyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione

References

1. Xiyao Cheng, et al. Nat Commun. 2022 Feb 28;13(1):1087.

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