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Chemical Structure : HA130
CAS No.: 1229652-21-4
Catalog No.: PC-45610Not For Human Use, Lab Use Only.
HA130 (HA-130) is a potent and selective inhibitor of autotaxin with IC50 of 28 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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HA130 (HA-130) is a potent and selective inhibitor of autotaxin with IC50 of 28 nM.
HA130 shows no effect on chymotryptic, caspase, and tryptic activities of the proteasome, alkaline phosphatase and a broad-spectrum PEDs (IC50>10 uM)。
HA130 inhibits ATX-driven melanoma cell migration and decreases circulating LPA levels in mice.
| M.Wt | 463.2858 | |
| Formula | C24H19BFNO5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 39 mg/mL |
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| Chemical Name/SMILES |
Boronic acid, B-[3-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]- |
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1. Albers HM, et al. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7257-62.
2. Zhang Y, et al. J Immunol. 2012 Oct 15;189(8):3914-24.
3. Lai SL, et al. Development. 2012 Dec 1;139(23):4439-48.
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