Chemical Structure : HBX-90659
CAS No.: 924296-19-5
Catalog No.: PC-72535Not For Human Use, Lab Use Only.
HBX-90659 (compound 22 e) is a potent, selective USP8 inhibitor with IC50 of 0.28 uM, with no effect on USP7 (IC50 of >100 uM).
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HBX-90659 (compound 22 e) is a potent, selective USP8 inhibitor with IC50 of 0.28 uM, with no effect on USP7 (IC50 of >100 uM).
HBX-90659 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 uM.
M.Wt | 275.27 | |
Formula | C15H9N5O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
9-(Ethoxyimino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile |
1. Matteo Colombo, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.
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