You are here:Home-Chemical Inhibitors & Agonists-Proteasome/Ubiquitin-Deubiquitinase (DUB)-HBX-90659
HBX-90659

Chemical Structure : HBX-90659

CAS No.: 924296-19-5

HBX-90659 (HBX90659, compound 22e, USP8-IN-22e)

Catalog No.: PC-72535Not For Human Use, Lab Use Only.

HBX-90659 (compound 22 e) is a potent, selective USP8 inhibitor with IC50 of 0.28 uM, with no effect on USP7 (IC50 of >100 uM).

Packing Price Stock Quantity
5 mg $158 In stock
10 mg $248 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

HBX-90659 (compound 22 e) is a potent, selective USP8 inhibitor with IC50 of 0.28 uM, with no effect on USP7 (IC50 of >100 uM).
HBX-90659 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 uM.

Physicochemical Properties

M.Wt 275.27
Formula C15H9N5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

9-(Ethoxyimino)-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile

References

1. Matteo Colombo, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: