HIF1-IN-2 |CAS:159915-87-4 Probechem Biochemicals

Chemical Structure : HIF1-IN-2

HIF1-IN-2

Catalog No.: PC-70269Not For Human Use, Lab Use Only.

HIF1-IN-2 is a potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB.

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Biological Activity

HIF1-IN-2 is a potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB.
HIF1-IN-2 robustly induces PGK1 and Enolase 1 expression, also inhibit endogenous HIF-1 targets.

Physicochemical Properties

M.Wt	453.583
Formula	C26H35N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-2-(2-((4-((E)-1-(butoxyimino)propyl)-2,5-dimethylphenoxy)methyl)phenyl)-2-(methoxyimino)-N-methylacetamide

References

1. Lin X, et al. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):174-9.

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HIF1-IN-2

Biological Activity

Physicochemical Properties

References

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