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HJB97

Chemical Structure : HJB97

CAS No.: 2093391-24-1

HJB97 (HJB 97, HJB-97)

Catalog No.: PC-60104Not For Human Use, Lab Use Only.

HJB-97 (HJB97) is a potent BET bromodomian inhibitor with IC50 of 3-7 nM for BRD2/3/4 BD1 and BD2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    HJB-97 (HJB97) is a potent BET bromodomian inhibitor with IC50 of 3-7 nM for BRD2/3/4 BD1 and BD2.

    Physicochemical Properties

    M.Wt 500.563
    Formula C26H28N8O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-((3-cyclopropyl-1-ethyl-1H-pyrazol-5-yl)amino)-7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-N-methyl-9H-pyrimido[4,5-b]indole-2-carboxamide

    References

    1. Zhou B, et al. J Med Chem. 2017 Mar 24. doi: 10.1021/acs.jmedchem.6b01816.

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