HL389 | CRL4 DCAF11 ligand | Probechem Biochemicals

Chemical Structure : HL389

Catalog No.: PC-22414Not For Human Use, Lab Use Only.

HL389 is a molecular glue acting as recruitment moiety for CRL4 DCAF11 and could be used for developed alkenyl oxindole-based PROTAC molecules.

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Biological Activity

HL389 is a molecular glue acting as recruitment moiety for CRL4 DCAF11 and could be used for developed alkenyl oxindole-based PROTAC molecules.

M.Wt	498.30
Formula	C22H19BrF3NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	tert-butyl (Z)-2-(4-bromo-2-((2-oxo-6-(trifluoromethyl)indolin-3-ylidene)methyl)phenoxy)acetate

1. Wang Y, et al. PLoS Biol. 2024 May 20;22(5):e3002550.