Catalog No.: PC-45513Not For Human Use, Lab Use Only.
HQ-415 is a derivative of 8-hydroxyquinoline that has selectivity for rescuing the distinct toxicities caused by the expression of TDP-43 with EC50 of 15 uM, α-synuclein or polyglutamine proteins.
HQ-415 is a derivative of 8-hydroxyquinoline that has selectivity for rescuing the distinct toxicities caused by the expression of TDP-43 with EC50 of 15 uM, α-synuclein or polyglutamine proteins.
HQ-415 shows distinct metal chelation and ionophore activities.
HQ-415 strongly synergized with CQ at multiple concentrations in cells expressing α-Syn in proteotoxicity models.
