HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells.
HSP27 inhibitor J2 enhances cancer cell sensitization with cisplatin, cisplatin-induced lung cancer cell growth inhibition in vitro.
HSP27 inhibitor J2 significantly inhibits immune cell infiltration in lung tissue, attenuates radiation-induced pulmonary inflammation in mice.
