You are here:Home-Chemical Inhibitors & Agonists-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-HSP27 inhibitor J2
HSP27 inhibitor J2

Chemical Structure : HSP27 inhibitor J2

CAS No.: 2133499-85-9

HSP27 inhibitor J2

Catalog No.: PC-63191Not For Human Use, Lab Use Only.

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells.

Packing Price Stock Quantity
2 mg $158 In stock
5 mg $278 In stock
10 mg $428 In stock
25 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: 99.5% (HPLC) Select Batch:

Biological Activity

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells.
HSP27 inhibitor J2 enhances cancer cell sensitization with cisplatin, cisplatin-induced lung cancer cell growth inhibition in vitro.
HSP27 inhibitor J2 significantly inhibits immune cell infiltration in lung tissue, attenuates radiation-induced pulmonary inflammation in mice.

Physicochemical Properties

M.Wt 264.295
Formula C13H12O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-hydroxy-2-methyl-7-(thiiran-2-ylmethoxy)-4H-chromen-4-one

References

1. Kim JY, et al. Sci Rep. 2018 Mar 8;8(1):4189.

2. Hwang SY, et al. Eur J Med Chem. 2017 Oct 20;139:892-900.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: