Catalog No.: PC-43120Not For Human Use, Lab Use Only.
HSP70-IN-27c is a potent, irreversible inhibitor of Hsp70 without Hsp 90 binding activity, inhibits growth of Kasumi-1 AML cells with IC50 of 2.3 uM, and inhibits Caspase-3,7 activation in MOLM13 AML cells with IC50 of 1.9 uM.
HSP70-IN-27c is a potent, irreversible inhibitor of Hsp70 without Hsp 90 binding activity, inhibits growth of Kasumi-1 AML cells with IC50 of 2.3 uM, and inhibits Caspase-3,7 activation in MOLM13 AML cells with IC50 of 1.9 uM.
HSP70-IN-27c inhibits HER2 and Raf-1 steady-state levels, PARP cleavage in SKBr3 breast cancer cells with IC50 of about 1.5 uM.
HSP70-IN-27c induces apoptosis in MDA-MB-468 cells.
