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Chemical Structure : HU-210
Catalog No.: PC-22159Not For Human Use, Lab Use Only.
HU-211 is a functional N-methyl-D-aspartate receptor blocker with IC50 of 6-10 uM for glutamate- or glycine-induced binding.
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HU-211 is a functional N-methyl-D-aspartate receptor blocker with IC50 of 6-10 uM for glutamate- or glycine-induced binding.
HU-211 is a synthetic terpene-based cannabinoid devoid of central cannabinoid (CB1) and peripheral cannabinoid (CB2) agonist activity.
HU-211 also has anti-inflammatory properties derived through inhibition of NF-κB and the resulting decreases in cytokines such as TNF-α and interleukin-6.
HU-211 induces stereotype and locomotor hyperactivity in mice and tachycardia in rat, effects typically caused by NMDA receptor antagonists.
HU-211 is also a potent blocker of NMDA-induced tremor, seizures, and lethality in mice.
| M.Wt | 386.58 | |
| Formula | C25H38O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Feigenbaum JJ, et al. Eur J Pharmacol. 1989 Oct 4;169(1):159-65.
2. Shohami E, et al. J Neurotrauma. 1993 Summer;10(2):109-19.
3. Feigenbaum JJ, et al. Proc Natl Acad Sci U S A. 1989 Dec;86(23):9584-7.
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