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Chemical Structure : HX531
CAS No.: 188844-34-0
Catalog No.: PC-20776Not For Human Use, Lab Use Only.
HX531 is a potent, pan RXR antagonist with IC50 of 18 nM on retinoidal activity in HL-60 cell assays, HX531 also is a partial PPARγ inhibitor and ameliorates diet-induced obesity and type 2 diabetes.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $198 | In stock | |
| 25 mg | $348 | In stock | |
| 50 mg | $588 | In stock | |
| 100 mg | Get quote | ||
| 1 g | Get quote |
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HX531 is a potent, pan RXR antagonist with IC50 of 18 nM on retinoidal activity in HL-60 cell assays, HX531 also is a partial PPARγ inhibitor and ameliorates diet-induced obesity and type 2 diabetes.
| M.Wt | 483.57 | |
| Formula | C29H29N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
O=C(O)C1=CC=C(C2=NC3=CC([N+]([O-])=O)=CC=C3N(C)C4=CC5=C(C(C)(C)CCC5(C)C)C=C42)C=C1 |
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1. M Ebisawa, et al. Chem Pharm Bull (Tokyo). 1999 Dec;47(12):1778-86.
2. T Yamauchi, et al. J Clin Invest. 2001 Oct;108(7):1001-13.
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