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Chemical Structure : Halofuginone
CAS No.: 55837-20-2
Catalog No.: PC-49610Not For Human Use, Lab Use Only.
Halofuginone (RU-19110) is a small molecule febrifugine analog targeting the Plasmodium falciparum prolyl-tRNA synthetase (PfcPRS, Ki=18.3 nM), inhibits wildtype Dd2 strain of P. falciparum with EC50 of 0.5 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $428 | In stock | |
| 100 mg | Get quote |
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Halofuginone (RU-19110) is a small molecule febrifugine analog targeting the Plasmodium falciparum prolyl-tRNA synthetase (PfcPRS, Ki=18.3 nM), inhibits wildtype Dd2 strain of P. falciparum with EC50 of 0.5 nM.
| M.Wt | 414.68 | |
| Formula | C16H17BrClN3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
7-bromo-6-chloro-3-(3-((2S,3R)-3-hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one |
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1. Jonathan D Herman, et al. Sci Transl Med. 2015 May 20;7(288):288ra77.
2. Jiang S, et al. Antimicrob. Agents Chemother. 2005;49:1169–1176.
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