Heparanase-IN-2

Chemical Structure : Heparanase-IN-2

Catalog No.: PC-73272Not For Human Use, Lab Use Only.

Heparanase-IN-2 is a potent, small molecule Heparanase (Hpse) inhibitor with IC50 of 0.12 uM.

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Biological Activity

Heparanase-IN-2 is a potent, small molecule Heparanase (Hpse) inhibitor with IC50 of 0.12 uM.
Heparanase-IN-2 decreases the mRNA levels of genes encoding for proangiogenic factors, such as FGF1/2, VEGF, and MMP-9.

Physicochemical Properties

M.Wt	763.496
Formula	C38H20Cl2N4O10
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2,2'-((isophthaloylbis(azanediyl))bis(3-chloro-4,1-phenylene))bis(1,3-dioxoisoindoline-5-carboxylic acid)

References

1. Daniele Pala, et al. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1685-1696.

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Heparanase-IN-2

Biological Activity

Physicochemical Properties

References

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