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Heterochromatin protein 1 inhibitor (R)-18

Chemical Structure : Heterochromatin protein 1 inhibitor (R)-18

CAS No.:

Heterochromatin protein 1 inhibitor (R)-18

Catalog No.: PC-25711Not For Human Use, Lab Use Only.

Heterochromatin protein 1 inhibitor (R)-18 is a small-molecule inhibitor of heterochromatin protein 1 (HP1), inhibits the HP1/H3K9me3 interaction with IC50 of 18.1 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Heterochromatin protein 1 inhibitor (R)-18 is a small-molecule inhibitor of heterochromatin protein 1 (HP1), inhibits the HP1/H3K9me3 interaction with IC50 of 18.1 uM.

Physicochemical Properties

M.Wt 340.38
Formula C19H20N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-(4-nitrobenzyl)pyrrolidine

References

1. Tokuyama A, et al. Bioorg Med Chem Lett. 2025 Nov 9:130469.

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